Intravenous Immunoglobulin Therapy: Treatment Approaches, Product Selection, and Administration Considerations

Recorded On: 06/13/2018

Intravenous immunoglobulin (IVIg) therapy is a life-saving treatment for patients with primary immune deficiency diseases. More than 75% of IVIg therapy administered in the United States is for patients with autoimmune and inflammatory diseases. However, indications for use continue to increase.  In this session, we will discuss the mechanism of action of immunoglobulins, the use of IVIg therapy in certain disease states, and dosing strategies. Current standardization of product selection, approaches to dosing, and administration, which have had a positive impact on patient safety, will also be considered.  

Learning Outcomes:  At the conclusion of this presentation, learners will be able to:

  • Verbalize 3 diagnoses for which intravenous immunoglobulin therapy is used.
  • Discuss the mechanism of action of immunoglobulins.
  • Describe approaches to dosing and administration.


Amy Clarke, RN, IgCN

Director of Nursing Clinical Program Services

Amy Clarke, RN, IgCN, is the director of nursing clinical program services for Diplomat Specialty Infusion Group. Involved in specialty and home infusion services since 1994, she has performed more than 2,000 intravenous and subcutaneous infusions. Ms. Clarke has delivered numerous presentations on immunoglobulin administration, including continuing education sessions for the National Home Infusion Association and the Immunoglobulin Nursing Society (IgNS). She is the immediate past president of IgNS. 

CRNI® RUs: This session has been approved for 1 CRNI® recertification unit and meets the non INS Meeting criteria.

Contact Hours: This session has been approved for 1 contact hour

Expiration date for receipt of contact hours: June 13, 2021

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